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Too many of us are not treated with respect by our loved ones. How many of us allow our family

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

and friends to treat us badly? How many of us will do anything to get the approval of our fathe

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r, mother, sibling, friend, boss, coworker, etc?

My son has been seeing a counselor to deal wi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

th his issue of wanting so much to be with his father that he will allow himself to be mistre

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ated. He wants so much to win his father's love and respect that he will put up with horrible e

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

motional abuse by his step mother. To him, it was worth this to see his father. He is now reali

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

zing that he does not have to tolerate this and that he should insist on being treated with res

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

pect. This is very hard for him, but he is very close to confronting his father about this.

Mo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

st of us have issues such as this to deal with. We spend our whole lives trying to get our Fath

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

er's approval, but it never seems to come. It is very hard for us to realize that it never will

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

. It is hard for us to say 'Enough! If you can't respect me, I don't want you around.'

My pare

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

nts died when I was a young adult and I do not have this issue with my parents. I only recently

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

realized that I have this issue with my siblings. This was like a slap in the face. Here I was

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

working with my son on insisting on being treated with respect, when I was not demanding respe

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ct from my siblings. It was a very enlightening experience.

I have decided that I will never a

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

gain allow anyone in my life who will not respect me. If they do not love me enough to do that,

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

then I do not want them around me. I deserve to be respected and will no longer allow myself

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

to be mistreated in that way. This decision has been very liberating.

Who in your life is treat

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ing you dis-respectfully? Are you still trying to get your Father, Mother, friend to respect yo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

u? How long will you continue to allow this treatment? Respect yourself enough to take a stand!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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