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    5 things you should never tell your boss.

    1. You never told me to do th
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    at!
    If you say that to your boss, you boss will not be happy with
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    hat and you will leave a bad impression in his mind. You boss may say th
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    at you are not pro active in your work and you should take the initiativ
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    to do it.

    2. Hey! Don’t yell at me!
    He can yell at you if he wan
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    s because he is the boss and you need him to pay you salary to feed your
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    family. But you yell at him, he will be angry and may say that you had
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    o EQ and he may fire you.

    3. I had to go home because I am tired.
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    If you say this to your boss, you boss will think that you did not work
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    hard enough and he may not give you important task for you to work on an
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    you may have difficult time to get yourself promoted.

    4. That’s not my
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    job.
    Oh! I see you have a job description, do you? No, you don’t!
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    he only job description that worth anything is the one that you said:” D
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    o whatever you need to do to make your boss think that without you he is
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    stuck.” Know what the person who say that will have to work at home in p
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    jamas.

    5. If you don’t give me a raise, I am quitting.
    If you said
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    that to your boss, your boss will say:” Fine you can leave now. A lot o
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    people are queuing up for this job and they are much cheaper.”

    Never e
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ver say the above to your boss or else you will be in trouble. Saying th
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    right words at the right time to your boss is important skill to master


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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