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There are people who have made me so mad, that I wish them bad luck . . . and worse. I envision all kinds of evil events befalling them. And ev

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ery time I hear that bad things happen to these people I rejoice, but at the same time I feel like maybe I’m less of a civilized person. Now, I

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ve found a release for my frustration, while still achieving revenge. That’s the best of both worlds.

I think it’s human nature that we seek r

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

venge when we have been ill treated by people. Most of us think about it and dream about it, but do nothing. But, just those actions of imagini

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

g make us feel better . . . without exacting punishment.

When we do hear of bad things happening to those people, we feel better. In reality,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ur enemies, just like us have bad things and good things happening to us all the time. It’s just that we search out the bad news because it mak

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s us feel better. Just wishing doesn’t really make it so, unfortunately. The bad news may make us feel better for a while, but it can leave a b

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d taste.

Even though we don’t actually make bad things happen, we always should try to do the right thing . . . like turning the other cheek a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

d loving our enemy. I’ve never been able to do that.

Now, however there is a study that gives me hope. It makes me think that I can be that be

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ter person, and still deliver hurtful results.

In a study financed by the Templeton Foundation, Dr. Herbert Benson of Harvard Medical School a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

d other scientists tested the effects of prayer for specific heart surgery patients. The prayers were for "a successful surgery with a quick, h

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ealthy recovery and no complications."

“In the largest study of its kind, researchers found that having people pray for heart bypa

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s surgery patients had no effect on their recovery. In fact, patients who knew they were being prayed for had a slightly higher rate of complic

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

tions.”
– Associated Press Story - Study: Prayer doesn't affect heart patients

What was interesting about the study wa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

that one of the control groups received prayer and the individual patients were told they were being prayed for and those were the ones who di

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

worse. They had the highest numbers of complications during recovery. The people praying were only told the initials of the patients, so they

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ould not really pray for particular people with them directly in mind. Just think about the damage they could have done, if they had been able

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

o associate names and faces. This produces all kinds of “good works” and possibilities.

No longer will I have to wish bad things for people. I

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

have an alternative. I think that I’m going to start praying for people I don’t like. It will no doubt make me a better person. Also, I’m going

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to send these people an anonymous postcard saying “I know what you’re going through, and I’m praying for you.” I’m sure they will appreciate it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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