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Your Space - More Negative Effects of Smoking: The Wrinkle Problem
Does smoking cause wrinkles?
It sure does!
Among the many negative effects of smoking, tobacco does s
It sure does!
Among the many negative effects of smoking, tobacco does s
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
peed up the aging process in one's skin.
And guess what? This damage is irreversible.
Why and how do
And guess what? This damage is irreversible.
Why and how do
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
s smoking attribute to this damage? When one smokes a cigarette, the blood vessels in the layers of on
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
's skin are restricted. Blood flow is impaired and oxygen and other important vitamins and nutrients ar
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
depleted. The skin's collagen and elastin are also damaged (these are fibers that give the skin its s
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
trength and elasticity). Therefore, the skin WILL wrinkle and sag in a most untimely manner.
Not to m
Not to m
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
ntion, the replication of one's smoking mannerisms (cigarette to mouth over and over again) creates mor
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
exposure to the toxins of a burning cigarette. Additionally, the facial expression one makes when smo
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
ing such as the squinting of eyes, or the puckering of the lips when inhaling, may contribute to wrinkl
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
es.
A known fact - smokers in their forties have as many wrinkles as a non smoker in his or her sixtie
A known fact - smokers in their forties have as many wrinkles as a non smoker in his or her sixtie
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
. Imagine that!
According to the Archives of Dermatological Research, a study proved that cigarette s
According to the Archives of Dermatological Research, a study proved that cigarette s
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
oking DID affect one's skin.
Cigarette smoke was pumped through a saline solution for two seconds ever
Cigarette smoke was pumped through a saline solution for two seconds ever
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
minute. Tiny drops of this solution was added to dishes of human cells called fibroblasts (cells that
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
produce collagen.)
After one day elapsed, the skin cells were tested. It was found the cells exposed
After one day elapsed, the skin cells were tested. It was found the cells exposed
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
to cigarette smoke produced less collagen by up to 40 percent. Which in turn is most likely what causes
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
premature wrinkles in smokers.
Less strength to the skin, more premature aging.
Do you really fancy g
Less strength to the skin, more premature aging.
Do you really fancy g
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ing to collect your kids from school as a premature 60 year old? This is not meant as scare-mongering -
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
this is fact. You are increasing the wrinkles on your face with every drag of the cigarette you take.
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
ou are damaging your face every day. This is a major negative effect of smoking, and if you want to lim
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
t the damage, quit the habit now.
Quite simple.
Among the many negative effects of smoking? Wrinkles
Quite simple.
Among the many negative effects of smoking? Wrinkles
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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