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What is the first image that pops into your mind when you think of the word meditation? A room with lighted candles and incense, sitting

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

down cross legged on the floor, palms up, and eyes closed? Well you’re pretty close to what most people imagine meditation to be.

Ok so

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ost of it is not entirely untrue of meditation, but it is not necessary the same always. Before we conjure up images of how meditation is

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

practiced let us first understand what meditation really is and why it is widely practiced the world over.

Meditation is a conscious re

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

axation. It is a process through which the mind reaches a state of serenity or bliss through deep concentration. If water can be used to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s an example then meditation can be explained this way; if you start pouring water from a pitcher into a glass, the first few drops would

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

be considered “concentration”, and once a steady flow is obtained that would be “meditation”. The first few unsteady drops and the small

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

splash they make are considered the distractions in concentration. A deeper state, which is the steady flow in the example, characterizes

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

meditation where the mind is free of distractions.

Stress is the number one reason why most people resort to meditation. Busy schedules

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

living life in the fast lane, demanding careers and higher expectations have led to soaring stress levels. Some have found solace in pre

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

cription drugs that have a “calming” effect to get rid of stress. However most of these forms of relaxation only provide fleeting relief

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and result in harmful side effects in the long run. After the medications wear off, it is back to the pit again. Since it is an afflictio

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

of the mind, the only cure lies in the mind itself.

So how does one go about practicing meditation? It is simpler than what most people

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

think it to be. First up you need to find a quiet spot, sit comfortably, relax your emotions and find an object or thought to meditate o

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

. It is important to just think of a single object or thought and concentrate on it. It is natural if you find that your mind keeps wande

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ing in the beginning, but you need to force your mind to discard all other thoughts that break your concentration. You can still be aware

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

of your surroundings, but you will find as your concentration deepens your surroundings will cease to exist.

Think of meditation as a k

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nd of spring cleaning for your mind and body, except you can do this everyday. People who have been through this will tell you that medit

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ation brings about a feeling of utter bliss where the mind is free and relaxed. Oh and if your wondering about the side effects of medita

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ion; let’s see, how about peace, tranquility and a feeling of completeness? Works for me, time you tried some of the goodies for yourself

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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