Your Space - Health and Fitness

The onset of winter brings with it the danger of influenza or flu, the disease is gradually turning out to be a perilous epidemic and leaves the patient in vulnera

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ble position. The phenomenal rise in people suffering from flu is also a matter of concern for experts.

Defining Influenza or Flu: Commonly occurring in wi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nters Influenza or flu is a viral infection of the nose, throat, bronchial tubes and lungs. There are two main types of mutating virus: A and B. Type A virus tends

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

to cause more severe illness than type B. Influenza affects people of all age groups but it is most Anyone can get influenza, but it is most serious in elderly, i

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n people with chronic underlying illnesses such as cancer, emphysema or diabetes or in those with weakened immune systems. The worst part of the disorder is its co

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tagiousness; the disorder is highly transmittable, even a slight contact with droplets from the nose and throat of an infected person during coughing and sneezing

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

is enough to get prone to the disorder.

Avian Flu and its Human transmission: Widely known as bird Flu, Avian influenza is an infectious disease of birds c

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

aused by type A strains of the influenza virus. The influence of Avian Flu viruses is not common in specie

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s except for birds and pigs but the incident occurring in Hongkong in 1997 was a setback. The H5N1 virus affected 18 people out of which 6 died. H5N1 is of particu

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

lar concern for several reasons. H5N1 mutates rapidly and has a documented propensity to acquire genes from viruses infecting other animal species. Its ability to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ause severe disease in humans has now been acknowledged on two occasions. Studies reveal that isolates from this virus have a high pathogenicity and can cause seve

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

re disease in humans.

Is Tamiflu a Savior?

Approved by the FDA on October 27, 1999 Roche's Tamiflu (Os

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eltamivir Phosphate) is a medicine to treat flu. Belonging to a group of medicines called Neuraminidase Inhibitors these medications attack the influenza virus and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

prevent it from spreading inside your body. Tamiflu is highly effectual in treating adults, adolescents, and pediatric patients 1year of age and older with the fl

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

u whose flu symptoms started within the last day or two. It is also handy in reducing the chance of getting the flu in people age 13 and older who have a higher c

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ance of getting the flu because they spend time with someone who has the flu. Tamiflu can also reduce the chance of getting the flu if there is a flu outbreak in

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

the community.

Why Tamiflu?

The fact that makes Tamiflu the best medication available against influenza is that it is anti-viral. Even antibiotics can kil

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

l bacteria but they are not effective against viral infection and since flu is a viral infection it deserves treatment through an anti-viral medication, which is T

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

amiflu. The product (Tamiflu) is a Neuraminidase Inhibitors and treats the cause of influenza infection by inhibiting the critical neuraminidase protein on the sur

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

face of the virus. Buy Tamiflu and rid your self from the dangerous consequences of Flu. Others common medications available for flu are Amantadine and Rimantadine

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.yourspace.org.ua/article/253043/yourspace-Roche-Tamiflu-The-Ultimate-Weapon-for-the-Treatment-of-Influenza.html">Roche Tamiflu: The Ultimate Weapon for the Treatment of Influenza</a>

BB link (for phorums):
[url=http://www.yourspace.org.ua/article/253043/yourspace-Roche-Tamiflu-The-Ultimate-Weapon-for-the-Treatment-of-Influenza.html]Roche Tamiflu: The Ultimate Weapon for the Treatment of Influenza[/url]

Looking for a way to get your newly published web site up and running with out having to pay an arm and a leg for advertising? Then advertise for free!

OK President Bush, tell me why an unwanted embryo is a sacred thing and a dead Iraqi or Lebanese baby is collateral damage. Doesn’t sound like a moral judgment call to me. More like culturally bigoted politics.

Chair massage is taught as a preventative tool for relief of discomfort. Certification in Chair Massage takes only a few weeks, and there are many schools, both traditional and alternative, to choose from. Most physical symptoms of pain can be attributed to a lack of circulation, and this is where chair massage is most helpful.

Tags

Links

Your Space - Roche Tamiflu: The Ultimate Weapon for the Treatment of Influenza

Related Articles: