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Contact lenses can change the way you see the world. Using lenses drastically alters your vision and appearance. But for maintaining the health of

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

your eyes and protecting your vision you need to care for your lenses. Protein deposits or fungal growth can prove detrimental to your eyes.

Once

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

you have had your eyes checked by the doctor and ordered your lenses, request your eye care professional to instruct you on how to care for your le

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nses. Educate yourself by reading articles and tips on web sites devoted to the care of vision health. Make a list of doubts you want to clear and

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

find out answers to the questions.

Many lens providers give a detailed booklet along with the lenses. Read the booklet thoroughly and understand w

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

hat needs to be done. Remember, lens care is not standard different kinds have a different regimen. So, the care required would depend on whether y

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

our lenses are daily wear, disposables, soft lenses, hard lenses, or continuous wear. Daily wear lenses must be removed at the end of the day, con

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

inuous wear lenses at the end of six days and disposable lenses must be discarded.

Basically lens care means:

1. Washing your hands thoroughly wi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

th mild soap, then rinsing the hands well and drying with a lint free towel before handling the lenses. Your hands must be free of pollutants and f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

oreign bodies at all times. Never use cold cream, cosmetics, face powder or lotions just before handling the lenses.

2. Always handle lenses with

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

your fingertips. Keep fingernails short and well filed.

3. After removal, the lenses must be cleaned, rinsed, and disinfected well. The solutions

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

used must be approved by the FDA and manufactured by reputable companies. Never compromise on quality, remember you must protect your eyes. Clean l

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

enses immediately after you remove them from the eyes.

4. The lens care solution must be fresh not expired and follow carefully the chemical syste

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

m of sterilization.

5. For rewetting lenses only use recommended solutions not saliva or any other alternative. Never lick your lens or use tap wa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

er.

6. Fix your routine and follow it carefully. Remove lens 1, clean, rinse, disinfect and then place in its chamber in the lens storage case. Th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

en repeat procedure for lens 2.

7. Lenses should always be completely immersed in disinfecting solution when not in use. Never leave lenses expose

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d to dust or air.

8. Learn the correct method of storing lenses.

9. If recommended use a lubricating solution while the lenses are in use. This w

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ill give comfort.

10. If you experience stickiness, discomfort, or any other problem immediately consult your doctor and replace the lenses. No le

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ns with bacterial or fungal growth should ever be worn.

If you experience any irritation from household cleaning fluids, gardening solutions, flyi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ng particles, or chemicals rinse your eyes well with tap water and go immediately to the doctor’s clinic or hospital. Treatment must not be delayed

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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