Your Space - Health and Fitness

Our teeth are important in maintaining good self-image. Have you lost your self confidence because of a swollen g

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

um or a wobbly tooth that seems to come off as you speak? These are also important in proper speech delivery, pro

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

per digestion and food appreciation. Dental hygiene plays a vital role in keeping the vitality of your teeth and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the surrounding tissues. The most prevalent of these diseases are dental decay and periodontal disease. Dental d

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ecay or dental caries is probably the most common human disorder. Dental caries and periodontal disease can be pr

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

vented by a successful dental hygiene program. A good dental hygiene program should include the following:

1. Pr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oper eating habits and good diet. Dental decay is caused by the breakdown of sugar into acid by bacteria that ar

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e naturally present in the human oral environment. These bacteria feed on starches and sugars. Acid is formed whe

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

bacteria act on starch or sugar. The acid formed causes enamel degradation, which is the starting point of any d

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ental caries. Artificially sweetened foods, drinks and chewing gum are better options

2. Proper regular tooth br

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

shing techniques. It is advised to brush the teeth two or three times a day, it is always better to brush after e

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

very meal and after taking any food in between. Using dental floss to remove food particles trapped in between th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e teeth is also a very important part of a good dental hygiene program. Dental floss can remove food particles lo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ged in between the teeth that sometimes even a good tooth brushing technique cannot accomplish.

3. A regular vis

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

it to the dentist is necessary in order to maintain and preserve your oral health. A visit to the dentist after e

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ery six months is recommended. Your dentist will have all the knowledge on how you can maintain good oral hygiene

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

. Always take care of your teeth and maintain that beautiful smile till you grow old.

Adequate knowledge about t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he importance of oral hygiene and how to keep the oral cavity clean and healthy through proper brushing and floss

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ng techniques is necessary in order to maintain a good and healthy oral environment. These, together with a regul

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ar visit to the dentist, will ensure you a good functioning set of teeth with healthy and well kept mouth tissues

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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