Your Space - Health and Fitness

Life expectancy has always been high in some remote corners of the globe. Some distant and isolated villages in China and Tibet for example, have always reported cases of folks livin

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g to over 100 years old. There are no official birth records to back up their claims but if ever you see photos of these people they really do appear to be extremely old.

So why is

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

it then that some cultures live longer than most others? Do they hold the secret to leading a long and healthy life? I don’t believe there’s a single answer to that question but healt

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hy diet, healthy lifestyle, exercise, positive outlook, faith, family and companionship must all be contributory factors.

As far as diet goes, it’s a well known fact that the best fo

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

od is natural and balanced produce. Fresh vegetables, whole grains, and fresh fruits are included in most healthy diets. Beans are pretty good for us too, and also nuts in moderation.

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Furthermore, just about any foods that contain omega-3 fatty acids are excellent for the health. A lot of people don’t know this but eggs which come from free range chickens contain

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

omega-3 fatty acids? Now, omega-3 fatty acids are also found in many cold water fish and in pecorino cheese. Red wine in moderation is also touted by some octogenarians as a key to li

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ving longer but like all alcoholic beverages it has to be in moderation.

Another big mistake we make is the huge portions that we serve ourselves all too often. Eating until we’re fi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t to burst takes an awful strain on the body’s digestive system. The smaller the portions the better, even if it means eating an extra meal or two a day. It's a whole lot easier on th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e body than cramming in one or two heavy meals that’s for sure. And smoking? No healthy article would be complete without some mention on the dangers of the tobacco weed. Cigarettes,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

pipes, cigars etc, make no contribution to longevity and even those folks that do live to a ripe old age as smokers, are certainly not as fit as they would have been if they hadn’t sm

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oked.

Social factors also play a part. Faith in a God or spiritual principle, long term friendships and a happy family all contribute towards lessening life's work and burdens and co

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nsequently play an important role in living healthier and longer lives.

I can’t stress enough how important an active lifestyle is. Many of us are far too deskbound or armchair-stuck

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

these days. It appears to be a normal part of a modern life style but it doesn’t have to be.

Take a country like Japan for example, where many people are still living rural lives fa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

r away from the concrete jungles of modern society. They don’t have all the creature comforts that many of us have come to depend on. There’s little automation in their daily chores

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

as they go out to fish, milk the cows and goats, mend the fences, chop wood, trim trees and hedgerows, roping and rounding up animals, and of course, doing all their cooking from fres

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

h organic produce. Phew! Sounds tough doesn’t it, and it is of course, but as they do these things throughout their lives it keeps them fit and healthy. Think about it, they are in t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he fresh air, they get daily physical exercise, they’re working amongst their friends and family members in close-knit communities, most have a faith in some kind of higher power, or

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

god, and all this equates to them being some of the oldest and healthiest living people on the face of the planet.

Just remember, there are things that we can all do personally to im

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

prove our chances of living, not only a longer life, but a healthier one too. Diet, exercise faith, and active participation in our communities can all help our wellbeing and purpose.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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